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18 Continued efficacy was confirmed in a similar study in which Psoriasis Area and Severity Index (PASI) score improvements of at least 50%, 75%, and 90% was shown to be achieved by increasing percentages of participants over a period of years

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Acknowledgements This work was supported by a project (HI21C0694, Development of treatment for intractable skin diseases using low-molecular compounds with enhanced Wnt/beta-catenin) funded by the Ministry of Health and Welfare, Republic of Korea and by the National Research Foundation of Korea(KRF) grant funded by the Korea government(MSIT) (RS-2025-16072747)