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They also promote NO production, which is required for cell death induction ( Arabidopsis PCD by promoting MPK6-mediated caspase-3-like activation ( CONCLUSION In plants, RNS and ROS synthesis is a routine requirement for cells to undergo PCD, these small molecules can act either synergistically or independently ( Figure 1 ), although the clear relationship of RNS and ROS in the process of cell death remains elusive

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This targeted delivery significantly increases local drug concentration while minimizing systemic toxicity