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Thus, excess GPx1 can promote cancer cells survival in a number of cancers by a number of different mechanisms, including promoting cell survival pathways, such as those mediated by Akt, and inhibiting apoptotic cell death [142–144, 148]

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Together, the above evidence suggests that adiponectin may exert neuroprotective and pro-neurogenic effects in the hippocampus through mechanisms such as inhibition of neuronal apoptosis and modulation of neuroinflammation