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The application of ZnCl 2 significantly increases the release of proinflammatory mediators, such as TNF-α, IL-6, and IL-1β, in microglia stimulated with lipopolysaccharide (LPS), suggesting that zinc may sensitize microglia to release these mediators by modulating ROS levels (Higashi et al., 2017[188])
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Veljaca M, Lesch CA, Pllana R, Sanchez B, Chan K, Guglietta A
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