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It is not known if RYBELSUS® will cause thyr oid tumors or a type of thyr oid cancer called medullary thyr oid carcinoma (MTC) in people Do not use RYBELSUS® if: you or any of your family have ever had MTC, or if you have an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) you have had a serious allergic reaction to semaglutide or any of the ingredients in RYBELSUS®