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If a patient does smoke on the day of surgery, it should be at least two hours before the procedure, according to the American Society of Regional Anesthesia and Pain Medicine, because smoking marijuana can “significantly increase heart rate and blood pressure within the two hours following use, and it may increase the patient’s risk of suffering a surgery-related heart attack.” It's also unclear when it’s safe to resume marijuana use following surgery

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Regulation of growth hormone (GH) secretion by different glutamate receptor subtypes in the rat