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CAL and Car@Deu treatments led to increased scratching bouts compared to the mice in the other groups ( Figure 8C )

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FIGURE 1 3 Glycolysis and MDR In the presence of a sufficient oxygen supply, the energy required for the growth of normally differentiated cells is provided mainly via OXPHOS, however, tumor cells prefer to use glycolysis to generate energy, a phenomenon also called the Warburg effect or aerobic glycolysis